27 to the Eye Care Center at AU Medical Center. I dont want to sound alarmist, the 74 year-old from Clearwater, S.C., begins, but I think my eyes might last longer than I do. Well, thats my job, Nussbaum said, chuckling. After battling diabetes for nearly 40 years, Lowe has developed diabetic retinopathy, a consequence of uncontrolled diabetes that can damage small blood vessels in the eye and is the leading cause of blindness among working-age adults. A researcher across campus from the clinic is looking at a different way of potentially blocking the inflammation that can lead to that damage through a potential new drug. Dr. Shruti Sharma of the Center for Biotechnology and Genomic Medicine has a $1.5 million grant from the National Eye Institute to look at basic research into blocking inflammation among epithelial cells in light-sensing retina in the eye, Sharma is looking at a well-known agent in inflammation called interleukin-6 that can affect those cells even though they lack the receptor normally needed for such interaction, an effect called trans-signaling. While that effect had been known for a while it is not something that researchers had focused on in the past, she said. Sharma is looking at an experimental drug that in her early work seems to have blocked that type of action in those cells, using it both in the lab in human cells in the same kind of environment that is there in the eye and in a mouse model of diabetes. The hope is to prevent the barrier disruption to the cells that can cause them to become leaky and create inflammation, an early hallmark of the disease. The mouse model allows Sharma to test the compound in both late and early stages of the disease to see if it she can prevent diabetic retinopathy from happening, she said. Separately, the compound is being tested in human clinical trials in rheumatoid arthritis, which is also promising, Sharma said.
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Avoiding.xposure to things that promote cataract formation can also help. Early diagnosis and treatment are key to preventing permanent vision problems. In the United States, age-related lens changes have been reported in 42% between the ages of 52 and 64, 54 60% between the ages 65 and 74, 55 and 91% between the ages of 75 and 85. 54 Cataracts affect nearly 22 million Americans age 40 and older. The choices for treating cataracts in children depend on how likely the cataracts are to interfere with the development of normal vision . Many people consider poor vision an inevitable fact of ageing, but cataract surgery is a simple, relatively painless procedure to regain vision. What can I do if I already have lost some vision from cataract? If you think you have a cataract, see an eye doctor for an exam to find out for sure. An after-cataract can develop months or years after cataract surgery.
On.his.age: Cataract surgery video A cataract is a clouding of the lens inside the eye, causing vision loss that cannot be corrected with glasses, contact lenses or corneal refractive surgery like LASIK . Cataract removal is one of the most common operations performed in the United States. Surgery is typically performed on an outpatient basis under local anaesthesia. But during middle age, most cataracts are small and do not affect vision. Under local anaesthesia, a surgeon performing phacoemulsification makes a small opening on the side of your cornea . A cataract is a clouding of the normally clear lens of the eye. For most adults, surgery is only needed when vision loss caused by a cataract affects your quality of life. Researchers from the University Zurich were the first to identify the chromosomal location and exact molecular defect in the coding region of the gene responsible for a childhood cataract. Diet, vegetarianism, and cataract risk. Mayo Clinic does not endorse companies or products. It develops slowly and eventually interferes with your vision. If you choose surgery, your eye care professional may refer you to a specialist to remove the cataract. June 11, 2013.